Taken together, these findings suggest that expression of human CD46 in mouse macrophages enhances production of IFN-/ in response to MV infection, and IFN-/ synergizes with IFN- to enhance NO production and restrict viral protein synthesis and virus replication. expressing intact human CD46, viral protein synthesis and development of cytopathic effects were suppressed. Pretreating the … Continue reading Taken together, these findings suggest that expression of human CD46 in mouse macrophages enhances production of IFN-/ in response to MV infection, and IFN-/ synergizes with IFN- to enhance NO production and restrict viral protein synthesis and virus replication